Endocrine Abstracts

Introduction: Thionamides are first line treatment in the management of thyrotoxicosis; nevertheless several weeks of treatment is needed before euthyroidism is restored. This delayed and gradual action makes thionamides insufficient as sole treatment when acute control of the hyperthyroid status is mandatory, hence the need for potent yet rapid acting adjuvant antithyroid agent. Lithium is a monovalent cation that inhibits thyroid iodine uptake and hormone release with maximu...

A 39-year-old man was referred to the endocrinology clinic with a suspected phaeochromocytoma. He had a history of hypertension, episodic flushing and erectile dysfunction. He denied any recreational drugs abuse. His past medical history included primary hypogonadism of unknown cause and hypertension. He was on ramipril 5 mg od, atenolol 50 mg od and susatnon injections.Clinical examination was unremarkable away from BMI of 35, facial flushing and raised...

A 39-year-old man was referred to our department with an incidental finding of low blood glucose. He had presented to rheumatology with non-traumatic left knee pain and swelling. He had a longstanding history of obstructive sleep apnoea and hiatus hernia. He had not been taking any medications. Examination was unremarkable apart from tender left knee with an effusion. A diagnosis of reactive arthritis was made. An incidental finding of low blood glucose (2.7 mmol/l-normal 3.4&...

Introduction: Traumatic brain injury (TBI) is the leading cause of death and disability in young adults. It is important to recognise pituitary dysfunction following TBI as it can cause significant morbidity.Methods: 179 TBI patients (137 males) age 41.0±15.7 years (17.6–88.1 years) attended Charing Cross Hospital clinic (July 2009–August 2011). Median time since TBI was 0.27years (0.05–46.5 years, 26% >1 years). 34% had an intrac...